RICT 2019

Interfacing Chemical Biology and Drug Discovery

55th International Conference on Medicinal Chemistry

 Nantes, France    July 3-5, 2019

Plenary Speakers

Revisiting Freidinger Lactam for the Development of Bioactive Foldamers

Prof. Muriel AMBLARD
Prof. Muriel AMBLARD
CNRS-UNIVERSTY OF MONTPELLIER I, Montpellier, France
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Chemical Physiology of Antibody Conjugates and Natural Products

Dr Goncalo BERNARDES
Dr Goncalo BERNARDES
INSTITUTO DE MEDICINA MOLECULAR, PORTUGAL & UNIVERSITY OF CAMBRIDGE, Cambridge, United Kingdom
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Complex Glycans in Health and Disease

Prof. Geert-Jan BOONS
Prof. Geert-Jan BOONS
UTRECHT UNIVERSITY, Utrecht, The Netherlands
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Modulating Different Components of the Ubiquitin System with Small Molecules and Cyclic Peptides

Prof. Ashraf BRIK
Prof. Ashraf BRIK
TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY, Haifa, Israel
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The Influence of Free Ligand Conformations on Mcl-1 PPI Inhibition

Dr Rodrigo CARBAJO
Dr Rodrigo CARBAJO
ASTRAZENECA, Cambridge, United Kingdom
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Carbohydrate-Lectin Interactions - What makes them unique?

Prof. Dr Beat ERNST
Prof. Dr Beat ERNST
UNIVERSITY OF BASEL, Basel, Switzerland
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Empowering Cancer Target Validation with High Quality Chemical Probes

Dr Ingo HARTUNG
Dr Ingo HARTUNG
BAYER HEALTHCARE, Berlin, Germany
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Identification of S 64315, a potent and selective Mcl-1 inhibitor through fragment-based drug discovery

Dr Andras KOTSCHY
Dr Andras KOTSCHY
SERVIER RESEARCH INSTITUTE OF MEDICINAL CHEMISTRY, Budapest, Hungary
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Increasing Brain Exposure of Therapeutic Antibodies

Dr Dominique LESUISSE
Dr Dominique LESUISSE
SANOFI, Chilly-Mazarin, France
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Massively multi-target Profile-QSAR: IC50 predictions comparable to 4-concentration experiments for most Novartis Assays

Dr Eric MARTIN
Dr Eric MARTIN
NOVARTIS, Emeryville, United States
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What Makes a Great Medicinal Chemist: Some Fresh Thoughts

Dr Mark MURCKO
Dr Mark MURCKO
RELAY THERAPEUTICS, Cambridge, United States
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Cysteine Arylation to Engineer, Deliver, and Discover Proteins

Prof. Bradley Lether PENTELUTE
Prof. Bradley Lether PENTELUTE
MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, United States
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Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 (SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA)

Dr Hasane RATNI
Dr Hasane RATNI
F. HOFFMANN-LA ROCHE LTD, Basel, Switzerland
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Chemical Biology of mRNA Modifications

Prof. Andrea RENTMEISTER
Prof. Andrea RENTMEISTER
UNIVERSITY OF MÜNSTER, Münster, Germany
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Click-Cleavable Antibody-Drug Conjugates

Dr Marc ROBILLARD
Dr Marc ROBILLARD
TAGWORKS PHARMACEUTICALS, Eindhoven, The Netherlands
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Reprogramming the Reactivity of Iron in Cancer

Dr Raphaël RODRIGUEZ
Dr Raphaël RODRIGUEZ
INSTITUT CURIE, Paris, France
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Title to be announced

Dr Marwin SEGLER
Dr Marwin SEGLER
BENEVOLENTAI, London, United Kingdom

Paul Ehrlich Award Lecture - Chemotype, Phenotype, Target

Prof. Herbert WALDMANN
Prof. Herbert WALDMANN
MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY, Dortmund, Germany
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Unlocking Drug Discovery Power through Collaborative Efforts between Academia and CRO : Bringing Novel Tankyrase Inhibitors towards the Clinic

Dr Anita WEGERT
Dr Anita WEGERT
MERCACHEM-SYNCOM, Nijmegen, The Netherlands
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Keynote Speakers

Therapeutic Potential of Macrocyclic ALK2 Inhibitors

Dr Pascal BENDERITTER
Dr Pascal BENDERITTER
ONCODESIGN, Dijon, France
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Protein Engineering for Preclinical Development

Dr Anne CHEVREL
Dr Anne CHEVREL
AFFILOGIC, Nantes, France
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Tackling a Unique S1 Protease by SBDD. Discovery of Highly potent & selective Factor D Inhibitors

Dr Edwige LORTHIOIS
Dr Edwige LORTHIOIS
NOVARTIS, Basel, Switzerland
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